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MEDICAL RESEARCH
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Studies show Irvine's Cortex therapy slows memory loss

AMPAKINE treatment may bring favorable results to patients suffering from Huntington's disease.

By Kristen SchottPublished: March 06, 2009 02:33 PM

Irvine-based Cortex Pharmaceuticals' AMPAKINE molecules could be beneficial during the treatment of memory loss in Huntington's disease, according to a recent study from UC Irvine professor Gary Lynch, who is also a scientific founder of the company.

The tests were performed in mice carrying the same genetic mutation found in humans that causes Huntington's, a hereditary brain disease in which specific brain cells die. It is characterized by the progressive deterioration of cognitive processes and memory.

The results demonstrated that treating the mice with CX929, a high-impact AMPAKINE – molecules that increase the strength of signals at connections between brain cells – produced increases in the brain's chemical processes for creating and storing memories.

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